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Corneal Collagen Cross-Linking (CXL)

Corneal collagen cross-linking (CXL) may be considered when there is objective progression or increased risk of keratoconus, and corneal topography/refraction indicates continuous deepening. The decision is influenced by factors such as corneal thickness and safety margins, corneal inflammation/dry

24-72h

Response window

Approx. $1,900

Treatment fee

Included support

  • +Hospital matching
  • +Record review
  • +Care coordination
  • +Travel support
  • +Interpretation support

Not included

  • -Treatment fee
  • -Travel costs
  • -Optional extras

Hospital consultation window

Peking Union Medical College Hospital - Beijing - Grade 3A

Ruijin Hospital - Shanghai - Grade 3A

West China Hospital - Chengdu - Grade 3A

Our service process

Let us coordinate the treatment journey with you.

1

How Corneal Collagen Cross-Linking (CXL) is performed

Corneal collagen cross-linking uses riboflavin (vitamin B2) and ultraviolet light irradiation to enhance the cross-linking strength of the corneal stroma. A common practice is to remove or retain the epithelium, then instill riboflavin to fully infiltrate the cornea, followed by ultraviolet light irradiation with a set energy; standard or accelerated protocols can be used, depending on corneal thickness and assessment. A therapeutic contact lens is placed after surgery to monitor pain, epithelial healing, and corneal transparency, with the goal of stabilizing the shape and slowing progressive deformation. The above is general health information and not medical advice; specific information is subject to specialist assessment and hospital protocols.

What is Corneal Collagen Cross-Linking (CXL)?

Corneal collagen cross-linking uses riboflavin (vitamin B2) and ultraviolet light irradiation to enhance the cross-linking strength of the corneal stroma. A common practice is to remove or retain the epithelium, then instill riboflavin to fully infiltrate the cornea, followed by ultraviolet light irradiation with a set energy; standard or accelerated protocols can be used, depending on corneal thickness and assessment. A therapeutic contact lens is placed after surgery to monitor pain, epithelial healing, and corneal transparency, with the goal of stabilizing the shape and slowing progressive deformation. The above is general health information and not medical advice; specific information is subject to specialist assessment and hospital protocols.

How is Corneal Collagen Cross-Linking (CXL) performed?

Step 1

How Corneal Collagen Cross-Linking (CXL) is performed

Corneal collagen cross-linking uses riboflavin (vitamin B2) and ultraviolet light irradiation to enhance the cross-linking strength of the corneal stroma. A common practice is to remove or retain the epithelium, then instill riboflavin to fully infiltrate the cornea, followed by ultraviolet light irradiation with a set energy; standard or accelerated protocols can be used, depending on corneal thickness and assessment. A therapeutic contact lens is placed after surgery to monitor pain, epithelial healing, and corneal transparency, with the goal of stabilizing the shape and slowing progressive deformation. The above is general health information and not medical advice; specific information is subject to specialist assessment and hospital protocols.

How Corneal Collagen Cross-Linking (CXL) is performed

Recovery process

Step 1

Recovery and stay

Including pre-operative assessment and early follow-up, it is generally recommended to stay for 5–10 days; the specific schedule is subject to the actual schedule of the hospital.

Recovery and stay

Request a free evaluation

Tell us about your Keratoconus case and we will help match you with the right hospital, specialist, and travel pathway.

Frequently asked questions

How do I get started?
Submit a free evaluation request with your diagnosis and records. The team reviews your case and suggests suitable next steps.
Do I need a visa to travel to China for treatment?
Many patients do. We can help explain what documents are normally needed for treatment travel planning.
Will there be a language barrier?
Medical interpretation can be arranged for consultations and treatment visits.
How much does treatment cost?
Costs depend on the procedure, hospital, and treatment pathway. A practical estimate is provided before travel.
What happens after I return home?
We can help coordinate remote follow-up and keep communication open with your care team.